PRESS RELEASE

March 14, 2003.

On March 13, 2003, during the 5th Sense of Contact event in Wageningen, The Netherlands, IBIS Technologies bv (Hengelo, The Netherlands), manufacturer of a complete Surface Plasmon Resonance (SPR) product line, launched its new SPR instrument, the IBIS iSPR. This instrument is the first commercial SPR imaging instrument that can be applied for High Throughput Screening (HTS). Its high optical resolution of 30 micrometer enables the simultaneous evaluation of more than 15.000 interactions on a single sensor, giving a daily capacity of more than 2 million analyses per instrument. Besides for HTS applications, the IBIS iSPR is an essential research instrument for every life science research laboratory. The IBIS iSPR is the perfect analysis instrument for combination with micro structured surfaces such as biochips and micro-arrays for genomic, proteomic and drug discover applications.

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The IBIS iSPR system operates with two monitors; one that displays the real time SPR-image and the other for instrument control and presentation of the processed data.

The IBIS iSPR is a novel imaging SPR instrument that allows the simultaneous monitoring of multiple binding interactions to the surface of one and the same sensor. This way, it can be used for real-time detection of the possible binding events to the many spots of a micoarray, for example. Thanks to it flexibility, the instrument can also be accommodated to be used as a, more conventional, 1- and 2-channel measurement set- up.

Two different instrument configurations are available:

For the 'basic configuration', the liquid system consists of a syringe pump, a drain pump and an autosampler with a double needle. This needle consists of an inner (inlet) needle that leads to a buffer bottle, and an outer (outlet) needle that leads via the drain pump to the waste bottle. The basic configuration instrument can be used in combination with a one-compartment cuvette, e.g. in the way the former 1-channel IBIS I was used, or for measuring on (micro) arrays. The system also can be used in combination with a negative pressure driven flow-cell, which is particularly useful in experiments with organic solvent.
For the 'plus configuration', the liquid system is extended with a second syringe pump. This configuration is very useful if one wants to use a 2-channel cuvette (comparable to the way the former IBIS II was used) or a positive pressure driven flow-cell. The IBIS iSPR is a novel imaging SPR instrument that allows the simultaneous monitoring of multiple binding interactions to the surface of one and the same sensor. This way, it can be used for real- time detection of the possible binding events to the many spots of a micoarray, for example. Thanks to it flexibility, the instrument can also be accommodated to be used as a, more conventional, 1- and 2-channel measurement set- up.
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