IBIS Optics for MX96 — Precision in Every Angle

Unlock the power of high-performance SPR imaging with the IBIS MX96’s advanced optics. Engineered to deliver exceptional sensitivity, the system uses a scanning-angle architecture that tracks the full SPR curve for each spot — giving you unrivaled dynamic range and precision.

 

Why IBIS Optics Matters

• Maximum Sensitivity: Thanks to the scanning-angle design, the MX96 achieves baseline noise below 0.5 RU (RMSD) — so you can detect even the subtlest binding events.
• Massive Dynamic Range: With a broad scanning angle (approximately 4°), you get a wide linear response window — from very weak signals to up to 30,000 RU.
• Ultra-Fine Spatial Resolution: With 25 µm lateral resolution, the optics let you define and monitor very small regions of interest.
• Unlimited Interaction Times: The system supports “unlimited” (> 3-day) association phases, enabling ultra-sensitive assays and long-term kinetics.

Built for Multiplex and High-Throughput

• You can run ligand arrays of varying sizes — all imaged in real time.
• The design supports hundreds of ROIs within a densely packed array template, maximizing multiplex throughput.
• With the sensitive optics and IBIS flow system, even low-molecular-weight compounds (>200 Da) can be reliably measured.

Engineered for Stability

• Hemisphere-based Kretschmann optics ensure consistent signal across the sensor surface, mitigating artifacts and ensuring reliable spot-to-spot comparisons.
• The temperature-controlled flow cell (Peltier) maintains thermal stability with remarkable precision (< 0.01 °C), ensuring reproducible measurements over extended runs.
• The optical setup is designed for long, unattended measurements — enabling deep kinetic studies, overnight runs, or continuous monitoring without user intervention.